Qbd-Based Approach to Optimize Niosomal Gel of Levosulpiride for Transdermal Drug Delivery

Qbd-Based Approach to Optimize Niosomal Gel of Levosulpiride for Transdermal Drug Delivery

Poor aqueous solubility besides extensive hepatic first effect significantly decreases the oral absorption of levosulpiride, which in turn minimizes its therapeutic effectiveness. Niosomes have been extensively investigated as a transdermal vesicular nanocarrier to increase the delivery of low perme...

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Bibliographic Details
Main Authors: Ahmed S. Alnaim, Hiral Shah, Anroop B. Nair, Vivek Mewada, Smit Patel, Shery Jacob, Bandar Aldhubiab, Mohamed A. Morsy, Rashed M. Almuqbil, Pottathil Shinu, Jigar Shah
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Gels
Subjects:
levosulpiride
niosomes
Box-Behnken design
evaluation
transdermal
pharmacokinetics
Online Access:https://www.mdpi.com/2310-2861/9/3/213

Internet

https://www.mdpi.com/2310-2861/9/3/213

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