Lysosome-related organelles promote stress and immune responses in C. elegans

Abstract Lysosome-related organelles (LROs) play diverse roles and their dysfunction causes immunodeficiency. However, their primordial functions remain unclear. Here, we report that C. elegans LROs (gut granules) promote organismal defenses against various stresses. We find that toxic benzaldehyde...

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Bibliographic Details
Main Authors: Gábor Hajdú, Milán Somogyvári, Péter Csermely, Csaba Sőti
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05246-7