Benzylic C−H acylation by cooperative NHC and photoredox catalysis
Direct acylation of sp3 C−H bonds in complex organic molecules is not well established compared to that of sp2 C−H bonds. Here, the authors report the combination of N-heterocyclic carbene (NHC) and photoredox catalysis for the direct and site-selective acylation of benzylic C−H bonds.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-22292-z |