Control of cellular Bcl-xL levels by deamidation-regulated degradation.

The cellular concentration of Bcl-xL is among the most important determinants of treatment response and overall prognosis in a broad range of tumors as well as an important determinant of the cellular response to several forms of tissue injury. We and others have previously shown that human Bcl-xL u...

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Bibliographic Details
Main Authors: So Hee Dho, Benjamin E Deverman, Carlo Lapid, Scott R Manson, Lu Gan, Jacob J Riehm, Rajeev Aurora, Ki-Sun Kwon, Steven J Weintraub
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3692414?pdf=render