RANKL signaling and osteoclastogenesis is negatively regulated by cardamonin.

Bone loss/resorption or osteoporosis is a disease that is accelerated with aging and age-associated chronic diseases such as cancer. Bone loss has been linked with human multiple myeloma, breast cancer, and prostate cancer and is usually treated with bisphosphonates, and recently approved denosumab,...

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Bibliographic Details
Main Authors: Bokyung Sung, Sahdeo Prasad, Vivek R Yadav, Subash C Gupta, Simone Reuter, Norio Yamamoto, Akira Murakami, Bharat B Aggarwal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23691159/?tool=EBI