TRPV1: A Target for Rational Drug Design

Transient Receptor Potential Vanilloid 1 (TRPV1) is a non-selective, Ca2+ permeable cation channel activated by noxious heat, and chemical ligands, such as capsaicin and resiniferatoxin (RTX). Many compounds have been developed that either activate or inhibit TRPV1, but none of them are in routine c...

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Bibliographic Details
Main Authors: Vincenzo Carnevale, Tibor Rohacs
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/9/3/52