TRPV1: A Target for Rational Drug Design
Transient Receptor Potential Vanilloid 1 (TRPV1) is a non-selective, Ca2+ permeable cation channel activated by noxious heat, and chemical ligands, such as capsaicin and resiniferatoxin (RTX). Many compounds have been developed that either activate or inhibit TRPV1, but none of them are in routine c...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-08-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8247/9/3/52 |