Sevoflurane postconditioning attenuates cardiomyocytes hypoxia/reoxygenation injury via PI3K/AKT pathway mediated HIF-1α to regulate the mitochondrial dynamic balance

Sevoflurane postconditioning attenuates cardiomyocytes hypoxia/reoxygenation injury via PI3K/AKT pathway mediated HIF-1α to regulate the mitochondrial dynamic balance

Abstract Background Myocardial ischemia-reperfusion injury (I/RI) is a major cause of perioperative cardiac-related adverse events and death. Studies have shown that sevoflurane postconditioning (SpostC), which attenuates I/R injury and exerts cardioprotective effects, regulates mitochondrial dynami...

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Bibliographic Details
Main Authors: Haiping Ma, Tianliang Hou, Jianjiang Wu, Jiyao Zhao, Haoran Cao, Maisitanguli. Masula, Jiang Wang
Format: Article
Language:English
Published: BMC 2024-05-01
Series:BMC Cardiovascular Disorders
Online Access:https://doi.org/10.1186/s12872-024-03868-1

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https://doi.org/10.1186/s12872-024-03868-1

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