Preparation and Characterization of Novel Polyelectrolyte Liposomes Using Chitosan Succinate Layered over Chitosomes: A Potential Strategy for Colon Cancer Treatment

Preparation and Characterization of Novel Polyelectrolyte Liposomes Using Chitosan Succinate Layered over Chitosomes: A Potential Strategy for Colon Cancer Treatment

Chitosan succinate is distinguished by its ability to shield the loaded drug from the acidic environment, localize and keep the drug at the colon site, and release the drug over an extended time at basic pH. The current study attempts to develop polyelectrolyte liposomes (PEL), using chitosan and ch...

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Bibliographic Details
Main Authors: Asmaa Mokhtar Yosef, Raghad Saleh Alqarni, Fai Yahya Sayd, Manar Saleem Alhawiti, Raghad M. Almahlawi, Kousalya Prabahar, Ubaidulla Uthumansha, Mansuor A. Alanazi, Mohamed El-Sherbiny, Nehal Elsherbiny, Mona Qushawy
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomedicines
Subjects:
chitosomes
colon drug delivery
HT-29 colon cancer cells
liposomal assisted drug delivery
polyelectrolyte liposomes
Online Access:https://www.mdpi.com/2227-9059/12/1/126

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https://www.mdpi.com/2227-9059/12/1/126

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