Epitope-coated polymer particles elicit neutralising antibodies against Plasmodium falciparum sporozoites
Abstract The current Malaria RTS,S vaccine is based on virus-like particles (VLPs) comprising the NANP repetitive epitopes from the cicumsporozoite protein (CSP) of Plasmodium falciparum. This vaccine has limited efficacy, only preventing severe disease in about 30% of vaccinated individuals. A more...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-11-01
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| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-021-00408-2 |