Sema3C Promotes the Survival and Tumorigenicity of Glioma Stem Cells through Rac1 Activation

Summary: Different cancer cell compartments often communicate through soluble factors to facilitate tumor growth. Glioma stem cells (GSCs) are a subset of tumor cells that resist standard therapy to contribute to disease progression. How GSCs employ a distinct secretory program to communicate with a...

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Bibliographic Details
Main Authors: Jianghong Man, Jocelyn Shoemake, Wenchao Zhou, Xiaoguang Fang, Qiulian Wu, Anthony Rizzo, Richard Prayson, Shideng Bao, Jeremy N. Rich, Jennifer S. Yu
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714009243