Riluzole Does Not Affect Hippocampal Synaptic Plasticity and Spatial Memory, Which Are Impaired by Diazepam in Rats

We have previously demonstrated that riluzole has anxiolytic-like effects in rats, without affecting spontaneous alternation performance in the Y-maze test. However, the effects of riluzole on hippocampal synaptic plasticity were still unclear. In this study, we showed that bath application of riluz...

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Bibliographic Details
Main Authors: Sachie Sasaki-Hamada, Hiroaki Sacai, Azusa Sugiyama, Takahiro Iijima, Akiyoshi Saitoh, Masatoshi Inagaki, Mitsuhiko Yamada, Jun-Ichiro Oka
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319303159