Riluzole Does Not Affect Hippocampal Synaptic Plasticity and Spatial Memory, Which Are Impaired by Diazepam in Rats

Riluzole Does Not Affect Hippocampal Synaptic Plasticity and Spatial Memory, Which Are Impaired by Diazepam in Rats

We have previously demonstrated that riluzole has anxiolytic-like effects in rats, without affecting spontaneous alternation performance in the Y-maze test. However, the effects of riluzole on hippocampal synaptic plasticity were still unclear. In this study, we showed that bath application of riluz...

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Bibliographic Details
Main Authors: Sachie Sasaki-Hamada, Hiroaki Sacai, Azusa Sugiyama, Takahiro Iijima, Akiyoshi Saitoh, Masatoshi Inagaki, Mitsuhiko Yamada, Jun-Ichiro Oka
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319303159

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