Early On-Treatment Prediction of the Mechanisms of Acquired Resistance to EGFR Tyrosine Kinase Inhibitors

Early On-Treatment Prediction of the Mechanisms of Acquired Resistance to EGFR Tyrosine Kinase Inhibitors

Background: Prediction of resistance mechanisms for epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) remains challenging. Thus, we investigated whether resistant cancer cells that expand shortly after EGFR-TKI treatment would eventually cause the resistant phenotype. Methods:...

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Bibliographic Details
Main Authors: Yu-ra Choi, Youngnam Cho, Seog-Yun Park, Sunshin Kim, Myungsun Shin, Yongdoo Choi, Dong Hoon Shin, Ji-Youn Han, Youngjoo Lee
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
lung CANCER
DRUG resistance
<i>EGFR</i> mutation
tyrosine kinase inhibitor
<i>C-MET</i> amplification
Online Access:https://www.mdpi.com/2072-6694/14/6/1512

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https://www.mdpi.com/2072-6694/14/6/1512

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