The crystal structure of bromide-bound GtACR1 reveals a pre-activated state in the transmembrane anion tunnel

The crystal structure of bromide-bound GtACR1 reveals a pre-activated state in the transmembrane anion tunnel

The crystal structure of the light-gated anion channel GtACR1 reported in our previous Research Article (Li et al., 2019) revealed a continuous tunnel traversing the protein from extracellular to intracellular pores. We proposed the tunnel as the conductance channel closed by three constrictions: C1...

Full description

Bibliographic Details
Main Authors: Hai Li, Chia-Ying Huang, Elena G Govorunova, Oleg A Sineshchekov, Adrian Yi, Kenneth J Rothschild, Meitian Wang, Lei Zheng, John L Spudich
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
channelrhodopsin
GtACR1
bromide binding
Guillardia theta
optogenetics
ACR
Online Access:https://elifesciences.org/articles/65903

Internet

https://elifesciences.org/articles/65903

Similar Items