Diversity and recognition efficiency of T cell responses to cancer.
Melanoma patients vaccinated with tumor-associated antigens frequently develop measurable peptide-specific CD8+ T cell responses; however, such responses often do not confer clinical benefit. Understanding why vaccine-elicited responses are beneficial in some patients but not in others will be impor...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2004-11-01
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Series: | PLoS Medicine |
Online Access: | http://europepmc.org/articles/PMC529423?pdf=render |