Radioresistance, DNA Damage and DNA Repair in Cells With Moderate Overexpression of RPA1
Molecular responses to genotoxic stress, such as ionizing radiation, are intricately complex and involve hundreds of genes. Whether targeted overexpression of an endogenous gene can enhance resistance to ionizing radiation remains to be explored. In the present study we take an advantage of the CRIS...
Main Authors: | Ilya O. Velegzhaninov, Elena S. Belykh, Elena E. Rasova, Yana I. Pylina, Dmitry M. Shadrin, Dmitry Yu. Klokov |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-07-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fgene.2020.00855/full |
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