Profiling sirolimus-induced inflammatory syndrome: a prospective tricentric observational study.

BACKGROUND: The use of the immunosuppressant sirolimus in kidney transplantation has been made problematic by the frequent occurrence of various side effects, including paradoxical inflammatory manifestations, the pathophysiology of which has remained elusive. METHODS: 30 kidney transplant recipient...

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Bibliographic Details
Main Authors: Fanny Buron, Paolo Malvezzi, Emmanuel Villar, Cécile Chauvet, Bénédicte Janbon, Laure Denis, Maria Brunet, Sameh Daoud, Rémi Cahen, Claire Pouteil-Noble, Marie-Claude Gagnieu, Jacques Bienvenu, François Bayle, Emmanuel Morelon, Olivier Thaunat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3538748?pdf=render