lncRNA-FMR6 directly binds SAV1 to increase apoptosis of granulosa cells in premature ovarian failure

Abstract Background A regulatory mechanism of lncRNA binding to protein has been detected in premature ovarian failure (POF). Therefore, this study was expected to illustrate the mechanism of lncRNA-FMR6 and SAV1 regulating POF. Methods Follicular fluid and ovarian granulosa cells (OGCs) from POF pa...

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Bibliographic Details
Main Authors: Dongqin Bao, Lei Gao, Haiyan Xin, Lie Wang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Ovarian Research
Subjects:
Online Access:https://doi.org/10.1186/s13048-023-01121-5