A Validated HPLC–Diode Array Detection Method for Therapeutic Drug Monitoring of Thiopurines in Pediatric Patients: From Bench to Bedside

A Validated HPLC–Diode Array Detection Method for Therapeutic Drug Monitoring of Thiopurines in Pediatric Patients: From Bench to Bedside

Thiopurine drugs are part of the therapeutic armamentarium for pediatric patients suffering from inflammatory bowel disease (IBD) and acute lymphoblastic leukemia (ALL). The therapeutic drug monitoring of these drugs, consisting of measurements of the thiopurine metabolites thioguanine nucleotides (...

Full description

Bibliographic Details
Main Authors: Martina Franzin, Debora Curci, Marianna Lucafò, Matteo Bramuzzo, Marco Rabusin, Antonella Fabretto, Riccardo Addobbati, Gabriele Stocco, Giuliana Decorti
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Metabolites
Subjects:
thiopurines
therapeutic drug monitoring
pediatric patients
Online Access:https://www.mdpi.com/2218-1989/12/12/1173

Internet

https://www.mdpi.com/2218-1989/12/12/1173

Similar Items