The Changes in Expression of Na<sub>V</sub>1.7 and Na<sub>V</sub>1.8 and the Effects of the Inhalation of Their Blockers in Healthy and Ovalbumin-Sensitized Guinea Pig Airways

The Changes in Expression of Na<sub>V</sub>1.7 and Na<sub>V</sub>1.8 and the Effects of the Inhalation of Their Blockers in Healthy and Ovalbumin-Sensitized Guinea Pig Airways

Background: The presented study evaluated the suppositional changes in the airway expression of Nav1.8 and Nav1.7 and their role in the airway defense mechanisms in healthy animals and in an experimental asthma model. Methods: The effects of the blockers inhalation on the reactivity of guinea pig ai...

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Bibliographic Details
Main Authors: Michaela Kocmalova, Ivana Kazimierova, Jana Barborikova, Marta Joskova, Sona Franova, Martina Sutovska
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Membranes
Subjects:
cough
bronchial hyperreactivity
ciliary beating frequency
asthma therapy
Nav1.8 channels
Online Access:https://www.mdpi.com/2077-0375/11/7/511

Internet

https://www.mdpi.com/2077-0375/11/7/511

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