Efficient Delivery of Curcumin by Alginate Oligosaccharide Coated Aminated Mesoporous Silica Nanoparticles and In Vitro Anticancer Activity against Colon Cancer Cells

Efficient Delivery of Curcumin by Alginate Oligosaccharide Coated Aminated Mesoporous Silica Nanoparticles and In Vitro Anticancer Activity against Colon Cancer Cells

We designed and synthesized aminated mesoporous silica (MSN-NH<sub>2</sub>), and functionally grafted alginate oligosaccharides (AOS) on its surface to get MSN-NH<sub>2</sub>-AOS nanoparticles as a delivery vehicle for the fat-soluble model drug curcumin (Cur). Dynamic light...

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Bibliographic Details
Main Authors: Chennan Liu, Fangyuan Jiang, Zifeng Xing, Lihong Fan, Yuan Li, Shaoning Wang, Junhong Ling, Xiao-Kun Ouyang
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceutics
Subjects:
pH-sensitive drug release
silica
brown algae oligosaccharides
curcumin
colon cancer cells
Online Access:https://www.mdpi.com/1999-4923/14/6/1166

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https://www.mdpi.com/1999-4923/14/6/1166

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