Comparative Pharmacokinetics Study of Icariin and Icariside II in Rats

To explore the pharmacokinetic properties of icariin (ICA) and icariside II (ICA II) following intragastric and intravenous administration in rats, a rapid and sensitive method by using ultra-performance liquid chromatography–tandem mass spectroscopy (UPLC-MS/MS) was developed and validated for the...

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Bibliographic Details
Main Authors: Tao Cheng, Yong Zhang, Tong Zhang, Lu Lu, Yue Ding, Yuan Zhao
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/12/19763