CD4+ T Cell Dependent B Cell Recovery and Function After Autologous Hematopoietic Stem Cell Transplantation

CD4+ T Cell Dependent B Cell Recovery and Function After Autologous Hematopoietic Stem Cell Transplantation

IntroductionHigh-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (auto-HSCT) represents a standard treatment regime for multiple myeloma (MM) patients. Common and potentially fatal side effects after auto-HSCT are infections due to a severely compromised immune syste...

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Bibliographic Details
Main Authors: Clarissa Heck, Sophie Steiner, Eva M. Kaebisch, Marco Frentsch, Friedrich Wittenbecher, Carmen Scheibenbogen, Leif G. Hanitsch, Axel Nogai, Philipp le Coutre, Lars Bullinger, Igor-Wolfgang Blau, Il-Kang Na
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
B cell defects
autologous hematopoiectic stem cell transplantation
T cell dependent B cell activation
immune reconstitution
multiple myeloma
secondary immunodeficiencies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.736137/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.736137/full

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