Target-dependent enrichment of virions determines the reduction of high-throughput sequencing in virus discovery.

Viral infections cause many different diseases stemming both from well-characterized viral pathogens but also from emerging viruses, and the search for novel viruses continues to be of great importance. High-throughput sequencing is an important technology for this purpose. However, viral nucleic ac...

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Bibliographic Details
Main Authors: Randi Holm Jensen, Sarah Mollerup, Tobias Mourier, Thomas Arn Hansen, Helena Fridholm, Lars Peter Nielsen, Eske Willerslev, Anders Johannes Hansen, Lasse Vinner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4390369?pdf=render