The streptozotocin-high fat diet induced diabetic mouse model exhibits severe skin damage and alterations in local lipid mediators

Background: Type 2 diabetes (T2D) can go undiagnosed for years, leading to a stage where produces complications such as delayed skin wound healing. Animal models have been developed in the last decades to study the pathological progression in this disease. Streptozotocin (STZ), that has a selective...

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Bibliographic Details
Main Authors: Alberto Leguina-Ruzzi, Rina Ortiz, Victoria Velarde
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Biomedical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417017303505