Kingella kingae PilC1 and PilC2 are adhesive multifunctional proteins that promote bacterial adherence, twitching motility, DNA transformation, and pilus biogenesis.

Kingella kingae PilC1 and PilC2 are adhesive multifunctional proteins that promote bacterial adherence, twitching motility, DNA transformation, and pilus biogenesis.

The gram-negative bacterium Kingella kingae is a leading cause of osteoarticular infections in young children and initiates infection by colonizing the oropharynx. Adherence to respiratory epithelial cells represents an initial step in the process of K. kingae colonization and is mediated in part by...

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Bibliographic Details
Main Authors: Alexandra L Sacharok, Eric A Porsch, Taylor A Yount, Orlaith Keenan, Joseph W St Geme
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010440

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https://doi.org/10.1371/journal.ppat.1010440

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