Amphotericin B-related nephrotoxicity in low-risk patients

INTRODUCTION: Amphotericin B (AmphoB) is the drug of choice for treatment of severe fungal illnesses; however, it is very nephrotoxic. Modified (less toxic) amphotericins are very expensive. In low-risk patients, saline loading would be enough to prevent significant loss of renal function. MATERIAL...

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Bibliographic Details
Main Authors: Roberto Herz Berdichevski, Luciano Billodre Luis, Letícia Crestana, Roberto Ceratti Manfro
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000200005&lng=en&tlng=en