Simple system for isothermal DNA amplification coupled to lateral flow detection.

Infectious disease diagnosis in point-of-care settings can be greatly improved through integrated, automated nucleic acid testing devices. We have developed an early prototype for a low-cost system which executes isothermal DNA amplification coupled to nucleic acid lateral flow (NALF) detection in a...

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Bibliographic Details
Main Authors: Kristina Roskos, Anna I Hickerson, Hsiang-Wei Lu, Tanya M Ferguson, Deepali N Shinde, Yvonne Klaue, Angelika Niemz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724848?pdf=render