Discovery of Acyl-Surugamide A2 from Marine <i>Streptomyces albidoflavus</i> RKJM-0023—A New Cyclic Nonribosomal Peptide Containing an N-ε-acetyl-L-lysine Residue

Discovery of Acyl-Surugamide A2 from Marine <i>Streptomyces albidoflavus</i> RKJM-0023—A New Cyclic Nonribosomal Peptide Containing an N-ε-acetyl-L-lysine Residue

We report the discovery of a novel cyclic nonribosomal peptide (NRP), acyl-surugamide A2, from a marine-derived <i>Streptomyces albidoflavus</i> RKJM-0023 (CP133227). The structure of acyl-surugamide A2 was elucidated using a combination of NMR spectroscopy, MS2 fragmentation analysis, a...

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Bibliographic Details
Main Authors: Zacharie A. Maw, Bradley Haltli, Jason J. Guo, Donna M. Baldisseri, Christopher Cartmell, Russell G. Kerr
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
<i>Streptomyces</i>
surugamide
cyclic peptide
nonribosomal peptide
acyl-surugamide A2
cyclic nonribosomal peptide
Online Access:https://www.mdpi.com/1420-3049/29/7/1482

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https://www.mdpi.com/1420-3049/29/7/1482

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