Heterogeneity and potential therapeutic insights for triple-negative breast cancer based on metabolic‐associated molecular subtypes and genomic mutations

Heterogeneity and potential therapeutic insights for triple-negative breast cancer based on metabolic‐associated molecular subtypes and genomic mutations

Objective: Due to a lack of effective therapy, triple-negative breast cancer (TNBC) is extremely poor prognosis. Metabolic reprogramming is an important hallmark in tumorigenesis, cancer diagnosis, prognosis, and treatment. Categorizing metabolic patterns in TNBC is critical to combat heterogeneity...

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Bibliographic Details
Main Authors: Lijuan Li, Nan Wu, Gaojian Zhuang, Lin Geng, Yu Zeng, Xuan Wang, Shuang Wang, Xianhui Ruan, Xiangqian Zheng, Juntian Liu, Ming Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Pharmacology
Subjects:
metabolic subtypes
triple-negative breast cancer
metabolic pathway
immune signature
immunotherapy response
mutation landscape
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1224828/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1224828/full

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