Subnormothermic Perfusion with H<sub>2</sub>S Donor AP39 Improves DCD Porcine Renal Graft Outcomes in an Ex Vivo Model of Kidney Preservation and Reperfusion

Subnormothermic Perfusion with H<sub>2</sub>S Donor AP39 Improves DCD Porcine Renal Graft Outcomes in an Ex Vivo Model of Kidney Preservation and Reperfusion

Cold preservation is the standard of care for renal grafts. However, research on alternatives like perfusion at higher temperatures and supplementing preservation solutions with hydrogen sulfide (H<sub>2</sub>S) has gained momentum. In this study, we investigated whether adding H<sub&...

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Bibliographic Details
Main Authors: Smriti Juriasingani, Aushanth Ruthirakanthan, Mahms Richard-Mohamed, Masoud Akbari, Shahid Aquil, Sanjay Patel, Rafid Al-Ogaili, Matthew Whiteman, Patrick Luke, Alp Sener
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomolecules
Subjects:
AP39
hydrogen sulfide
subnormothermic perfusion
kidney preservation
ischemia–reperfusion injury
donation after cardiac death
Online Access:https://www.mdpi.com/2218-273X/11/3/446

Internet

https://www.mdpi.com/2218-273X/11/3/446

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