A randomized trial of safety, acceptability and adherence of three rectal microbicide placebo formulations among young sexual and gender minorities who engage in receptive anal intercourse (MTN-035).

Efforts to develop a range of HIV prevention products that can serve as behaviorally congruent viable alternatives to consistent condom use and oral pre-exposure prophylaxis (PrEP) remain crucial. MTN-035 was a randomized crossover trial seeking to evaluate the safety, acceptability, and adherence t...

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Main Authors: Jose A Bauermeister, Clara Dominguez Islas, Yuqing Jiao, Ryan Tingler, Elizabeth Brown, Jillian Zemanek, Rebecca Giguere, Ivan Balan, Sherri Johnson, Nicole Macagna, Jonathan Lucas, Matthew Rose, Cindy Jacobson, Clare Collins, Edward Livant, Devika Singh, Ken Ho, Craig Hoesley, Albert Liu, Noel Kayange, Thesla Palanee-Phillips, Suwat Chariyalertsak, Pedro Gonzales, Jeanna Piper, MTN-035 Protocol Team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0284339