Dickkopf Proteins and Their Role in Cancer: A Family of Wnt Antagonists with a Dual Role

Dickkopf Proteins and Their Role in Cancer: A Family of Wnt Antagonists with a Dual Role

The Wnt signaling pathway regulates crucial aspects such as cell fate determination, cell polarity and organogenesis during embryonic development. Wnt pathway deregulation is a hallmark of several cancers such as lung, gastric and liver cancer, and has been reported to be altered in others. Despite...

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Bibliographic Details
Main Authors: Irina Giralt, Gabriel Gallo-Oller, Natalia Navarro, Patricia Zarzosa, Guillem Pons, Ainara Magdaleno, Miguel F. Segura, José Sánchez de Toledo, Lucas Moreno, Soledad Gallego, Josep Roma
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceuticals
Subjects:
Wnt signaling
Wnt antagonists
Dickkopf
DKK
Online Access:https://www.mdpi.com/1424-8247/14/8/810

Internet

https://www.mdpi.com/1424-8247/14/8/810

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