Novel Derivatives of Eugenol as a New Class of PPARγ Agonists in Treating Inflammation: Design, Synthesis, SAR Analysis and In Vitro Anti-Inflammatory Activity

Novel Derivatives of Eugenol as a New Class of PPARγ Agonists in Treating Inflammation: Design, Synthesis, SAR Analysis and In Vitro Anti-Inflammatory Activity

The main objective of this research was to develop novel compounds from readily accessed natural products especially eugenol with potential biological activity. Eugenol, the principal chemical constituent of clove (<i>Eugenia caryophyllata</i>) from the family Myrtaceae is renowned for i...

Full description

Bibliographic Details
Main Authors: Noor Fathima Anjum, Dhivya Shanmugarajan, B. R. Prashantha Kumar, Syed Faizan, Priya Durai, Ruby Mariam Raju, Saleem Javid, Madhusudan N. Purohit
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
eugenol derivatives
molecular docking
pharmacophore
structure–activity relationship
anti-inflammatory activity
Online Access:https://www.mdpi.com/1420-3049/28/9/3899

Internet

https://www.mdpi.com/1420-3049/28/9/3899

Similar Items