The role of α-tubulin tyrosination in controlling the structure and function of hippocampal neurons

The role of α-tubulin tyrosination in controlling the structure and function of hippocampal neurons

Microtubules (MTs) are central components of the neuronal cytoskeleton and play a critical role in CNS integrity, function, and plasticity. Neuronal MTs are diverse due to extensive post-translational modifications (PTMs), particularly detyrosination/tyrosination, in which the C-terminal tyrosine of...

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Bibliographic Details
Main Authors: Shirin Hosseini, Marco van Ham, Christian Erck, Martin Korte, Kristin Michaelsen-Preusse
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
microtubules
tubulin-tyrosine ligase
dendritic spine
synaptic plasticity
memory
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.931859/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.931859/full

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