Mono-(2-Ethylhexyl) Phthalate Promotes Pro-Labor Gene Expression in the Human Placenta.

Women exposed to phthalates during pregnancy are at increased risk for delivering preterm, but the mechanism behind this relationship is unknown. Placental corticotropin-releasing hormone (CRH) and cyclooxygenase-2 (COX-2) are key mediators of parturition and are regulated by the non-canonical NF-kB...

Full description

Bibliographic Details
Main Authors: Ximi K Wang, Monica Agarwal, Nataliya Parobchak, Alex Rosen, Anna M Vetrano, Aarthi Srinivasan, Bingbing Wang, Todd Rosen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4709041?pdf=render