Evaluation of the GABAA Receptor Expression and the Effects of Muscimol on the Activity of Wide Dynamic Range Neurons Following Chronic Constriction Injury of Sciatic Nerve in Rats

Evaluation of the GABAA Receptor Expression and the Effects of Muscimol on the Activity of Wide Dynamic Range Neurons Following Chronic Constriction Injury of Sciatic Nerve in Rats

Introduction: The modality of γ-aminobutyric acid type a receptors (GABAA) controls dorsal horn neuronal excitability and inhibits sensory information. This study aimed to investigate the expression of the GABAA receptor and the effects of its agonist muscimol on Wide Dynamic Range (WDR) neuronal ac...

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Bibliographic Details
Main Authors: Mehdi Sadeghi, Homa Manaheji, Jalal Zaringhalam, Abbas Haghparast, Samad Nazemi, Zahra Bahari, Seyed Mohammad Noorbakhsh
Format: Article
Language:English
Published: Iran University of Medical Sciences 2021-09-01
Series:Basic and Clinical Neuroscience
Subjects:
neuropathic pain
chronic constriction injury (cci)
γ-aminobutyric acid type a (gabaa) receptor
muscimol
wide dynamic range (wdr) neurons
Online Access:http://bcn.iums.ac.ir/article-1-1496-en.html

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http://bcn.iums.ac.ir/article-1-1496-en.html

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