CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes

CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes

Transient partial remission, a period of low insulin requirement experienced by most patients soon after diagnosis, has been associated with mechanisms of immune regulation. A better understanding of such natural mechanisms of immune regulation might identify new targets for immunotherapies that rev...

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Bibliographic Details
Main Authors: Aditi Narsale, Breanna Lam, Rosa Moya, TingTing Lu, Alessandra Mandelli, Irene Gotuzzo, Benedetta Pessina, Gianmaria Giamporcaro, Rhonda Geoffrey, Kerry Buchanan, Mark Harris, Anne-Sophie Bergot, Ranjeny Thomas, Martin J. Hessner, Manuela Battaglia, Elisavet Serti, Joanna D. Davies
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-01-01
Series:JCI Insight
Subjects:
Autoimmunity
Immunology
Online Access:https://doi.org/10.1172/jci.insight.136114

Internet

https://doi.org/10.1172/jci.insight.136114

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