A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila

Tauopathies are neurodegenerative diseases characterized by the presence of aggregates of abnormally phosphorylated Tau. Deciphering the pathophysiological mechanisms that lead from the alteration of Tau biology to neuronal death depends on the identification of Tau cellular partners. Combining gene...

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Bibliographic Details
Main Authors: Sébastien Feuillette, Camille Charbonnier, Thierry Frebourg, Dominique Campion, Magalie Lecourtois
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00068/full