Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation

Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation

Abstract Background Methotrexate (MTX) is used to treat graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Recently, a case was encountered in which the blood concentration of tacrolimus (TCR) at steady state increased after intravenous MTX adm...

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Bibliographic Details
Main Authors: Chiaki Inoue, Takehito Yamamoto, Hiroshi Miyata, Hiroshi Suzuki, Tappei Takada
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
Tacrolimus
Methotrexate
Hematopoietic stem cell transplantation
Therapeutic drug monitoring
Online Access:https://doi.org/10.1186/s40780-023-00306-w

Internet

https://doi.org/10.1186/s40780-023-00306-w

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