Assessment of the anti-nociceptive effects of fetal ventral mesencephalic tissue allografts in a rat model of hemi-Parkinson’s disease using fMRI

Extensive studies showed increased subjective pain sensitivity in Parkinson’s disease (PD), which appeared to be partially reversed by dopaminergic (DA) treatment. Although cell replacement represents an attractive therapeutic strategy, its potential for PD-related hyperalgesia remains unclear. We i...

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Main Authors: Chuang-Hsin Chiu, Shao-Ju Weng, Skye Hsin-Hsien Yeh, Yun-Ting Jhao, Hsien-Feng Chang, Wen-Sheng Huang, Cheng-Yi Cheng, Chun-Chang Yeh, Kuo-Hsing Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.948848/full