Across-proteome modeling of dimer structures for the bottom-up assembly of protein-protein interaction networks

Across-proteome modeling of dimer structures for the bottom-up assembly of protein-protein interaction networks

Abstract Background Deciphering complete networks of interactions between proteins is the key to comprehend cellular regulatory mechanisms. A significant effort has been devoted to expanding the coverage of the proteome-wide interaction space at molecular level. Although a growing body of research s...

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Bibliographic Details
Main Authors: Surabhi Maheshwari, Michal Brylinski
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Bioinformatics
Subjects:
Protein-protein interactions
Protein docking
Structural bioinformatics
Machine learning
Gene Ontology filters
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Online Access:http://link.springer.com/article/10.1186/s12859-017-1675-z

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http://link.springer.com/article/10.1186/s12859-017-1675-z

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