Redox-mediated carbon monoxide release from a manganese carbonyl—implications for physiological CO delivery by CO releasing moieties

Redox-mediated carbon monoxide release from a manganese carbonyl—implications for physiological CO delivery by CO releasing moieties

The dynamics of hydrogen peroxide reactions with metal carbonyls have received little attention. Given reports that therapeutic levels of carbon monoxide are released in hypoxic tumour cells upon manganese carbonyls reactions with endogenous H2O2, it is critical to assess the underlying CO release m...

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Bibliographic Details
Main Authors: Jacob A. Barrett, Zhi Li, John V. Garcia, Emily Wein, Dongyun Zheng, Camden Hunt, Loc Ngo, Lior Sepunaru, Alexei V. Iretskii, Peter C. Ford
Format: Article
Language:English
Published: The Royal Society 2021-11-01
Series:Royal Society Open Science
Subjects:
hydrogen peroxide
manganese carbonyl
CO releasing moiety
redox reaction
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.211022

Internet

https://royalsocietypublishing.org/doi/10.1098/rsos.211022

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