L-Selectin/CD62L Is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men

L-Selectin/CD62L Is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men

CD62L (L-Selectin) dependent lymphocyte infiltration is known to induce inflammatory bowel disease (IBD), while its function in the liver, especially in non-alcoholic steatohepatitis (NASH), remains unclear. We here investigated the functional role of CD62L in NASH in humans as well as in two mouse...

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Bibliographic Details
Main Authors: Hannah K. Drescher, Angela Schippers, Stefanie Rosenhain, Felix Gremse, Laura Bongiovanni, Alain de Bruin, Sreepradha Eswaran, Suchira U. Gallage, Dominik Pfister, Marta Szydlowska, Mathias Heikenwalder, Sabine Weiskirchen, Norbert Wagner, Christian Trautwein, Ralf Weiskirchen, Daniela C. Kroy
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
non-alcoholic steatohepatitis
NASH
CD62L
L-Selectin
insulin resistance
Online Access:https://www.mdpi.com/2073-4409/9/5/1106

Internet

https://www.mdpi.com/2073-4409/9/5/1106

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