Enterotoxigenic Bacteroides fragilis activates IL-8 expression through Stat3 in colorectal cancer cells

Enterotoxigenic Bacteroides fragilis activates IL-8 expression through Stat3 in colorectal cancer cells

Abstract Background Enterotoxigenic Bacteroides fragilis (ETBF) has been implicated in colorectal carcinogenesis through the actions of its toxin, B. fragilis toxin (BFT). Studies on colorectal cell lines have shown that treatment with BFT causes disruption of E-cadherin leading to increased express...

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Bibliographic Details
Main Authors: Rachel V. Purcell, Jessica Permain, Jacqueline I. Keenan
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Gut Pathogens
Subjects:
Enterotoxigenic Bacteroides fragilis
Toxin
Interleukin-8
IL-8
Stat3
E-cadherin
Online Access:https://doi.org/10.1186/s13099-022-00489-x

Internet

https://doi.org/10.1186/s13099-022-00489-x

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