Analysis of a Library of <i>Escherichia coli</i> Transporter Knockout Strains to Identify Transport Pathways of Antibiotics

Antibiotic resistance is a major global healthcare issue. Antibiotic compounds cross the bacterial cell membrane via membrane transporters, and a major mechanism of antibiotic resistance is through modification of the membrane transporters to increase the efflux or reduce the influx of antibiotics....

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Bibliographic Details
Main Authors: Lachlan Jake Munro, Douglas B. Kell
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/11/8/1129