Altered regulation of Akt signaling with murine cerebral malaria, effects on long-term neuro-cognitive function, restoration with lithium treatment.

Neurological and cognitive impairment persist in more than 20% of cerebral malaria (CM) patients long after successful anti-parasitic treatment. We recently reported that long term memory and motor coordination deficits are also present in our experimental cerebral malaria model (ECM). We also docum...

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Bibliographic Details
Main Authors: Minxian Dai, Brandi Freeman, Henry J Shikani, Fernando Pereira Bruno, J Elias Collado, Rolando Macias, Sandra E Reznik, Peter Davies, David Conover Spray, Herbert Bernard Tanowitz, Louis Martin Weiss, Mahalia Sabrina Desruisseaux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23082110/pdf/?tool=EBI