Unveiling immune checkpoint regulation: exploring the power of in vivo CRISPR screenings in cancer immunotherapy
Immune checkpoint inhibitors (ICIs) have revolutionized cancer immunotherapy by reinvigorating antitumor immune responses, but their efficacy remains limited in most patients. To address this challenge and optimize Immune check inhibitor treatment, understanding the underlying molecular intricacies...
Main Authors: | Yuxiang Wang, Athar Khalil, Amina Kamar, Mengyan Du, Trang Dinh, Christopher McFarland, Zhenghe Wang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-12-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2023.1304425/full |
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