Amarogentin promotes osteoblast differentiation in oestrogen-deficiency-induced osteoporosis rats by modulating the Nrf-2/MAPK/ERK signalling pathway

Introduction The beneficial effect of amarogentin in the management of osteoporosis was determined using in vivo and in vitro methods. Material and methods Experimental osteoporosis was induced in rats via bilateral ovariectomy. Rats were then treated for 5 weeks with amarogentin (50 and 100 mg/kg,...

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Bibliographic Details
Main Authors: Sirui Li, Xianlong Li, Feng He, Rui Jiao, Song Zhang, Zhihua Li
Format: Article
Language:English
Published: Termedia Publishing House 2019-11-01
Series:Archives of Medical Science
Subjects:
Online Access:https://www.archivesofmedicalscience.com/Amarogentin-promotes-osteoblast-differentiation-in-oestrogen-deficiency-induced-osteoporosis,111137,0,2.html