Micro-Environmental Stress Induces Src-Dependent Activation of Invadopodia and Cell Migration in Ewing Sarcoma

Metastatic Ewing sarcoma has a very poor prognosis and therefore new investigations into the biologic drivers of metastatic progression are key to finding new therapeutic approaches. The tumor microenvironment is highly dynamic, leading to exposure of different regions of a growing solid tumor to ch...

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Bibliographic Details
Main Authors: Kelly M. Bailey, Merlin Airik, Melanie A. Krook, Elisabeth A. Pedersen, Elizabeth R. Lawlor
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558616300987